Peptide Database

Peptide NameBuforin-2 [F10W] [P11A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC106H183N41O26

DescriptionStandard

        TRSSRAGLQWAVGRVHRLLRK
    

Molecular Weight2447.85 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.48

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.2612

GRAVY Index-0.65

Hydrophobic Moment 0.83

Boman Index-0.36

Instability Index62.29

Aliphatic Index 92.86

Aromaticity 0.0476

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1129.09

LogP -12.39

H-bond Donors 44.0

H-bond Acceptors 33.0

Rotatable Bonds 83.0

Heavy Atoms 173.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171334 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 27325

Activity6 μM

MethodMIC

RECORD: Rec_0385588 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity7 % hemolysis at 806 μM

MethodHemolysis