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MYP_072934
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Basic Information
Antimicrobial peptide Alo-1
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
34 amino acids
C150H228N50O48S6
Standard
Sequence
CIKNGNGCQPDGSQGNCCSRYCHKEPGWVAGYCR
Physicochemical Analysis
3692.11 Da
8.33
1.79
1.44
0.0526
-0.87
0.44
-0.15
23.72
22.94
0.0882
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1597.32
-22.65
60.0
57.0
117.0
254.0
7.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018445 VERIFIED: NO
Provenance & Taxonomy
Acrocinus longimatus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-18; 8-22; 17-33
Bio-Activity Profile
Antimicrobial Antifungal
C. glabrata
RECORD: Rec_0024988 VERIFIED: YES
Provenance & Taxonomy
Acrocinus longimanus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
1-18, 8-22, 17-33
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans IHEM 8060
64 μg/mL
MIC
PMID14661954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14661954/
RECORD: Rec_0106482 VERIFIED: YES
Provenance & Taxonomy
Acrocinus longimanus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
1-18, 8-22, 17-33
Bio-Activity Profile
Antimicrobial Antifungal
Candida glabrata patient 1
64 μg/mL
MIC
PMID14661954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14661954/
RECORD: Rec_0128077 VERIFIED: YES
Provenance & Taxonomy
Acrocinus longimanus [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0264223 VERIFIED: YES
Provenance & Taxonomy
Acrocinus longimanus [Animal]
AMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Non-hemolytic
PMID14661954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14661954/
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