Peptide Database

Peptide Namebeta-amyloid protein fragment:25-35

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC45H81N13O14S

DescriptionStandard

        GSNKGAIIGLM
    

Molecular Weight1060.27 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0690

GRAVY Index0.65

Hydrophobic Moment 0.03

Boman Index0.37

Instability Index15.18

Aliphatic Index 115.45

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 443.66

LogP -4.95

H-bond Donors 15.0

H-bond Acceptors 16.0

Rotatable Bonds 37.0

Heavy Atoms 73.0

Ring Count 0.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115284 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

PaperCasta?o J. M., Ghiso J., Prelli F., Gorevic P. D., Migheli A., Frangione B.. In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease beta-protein. Biochem. Biophys. Res. Commun., 141, 782-789, 1986. Evidence URLhttps://pubchem.ncbi.nlm.nih.gov/compound/10843733