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MYP_072875
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Basic Information
12-
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
6 amino acids
C32H62N14O7
Standard
Sequence
RRKKAP
Physicochemical Analysis
754.92 Da
12.00
3.76
3.55
0.6263
-2.77
0.18
-1.22
135.90
16.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
375.87
-3.87
14.0
11.0
26.0
53.0
1.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008708 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Vaccinia virus (Virus entry); HeLa
4.72 mOD/min
Plaque assay
PaperInhibition of Vaccinia virus entry by a broad spectrum antiviral peptide. | Altmann SE, Jones JC, Schultz-Cherry S, Brandt CR. | Virology. 2009 | PMID:19395056 PMID19395056 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19395056/
RECORD: Rec_0040441 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20100041604A1/en PatentUS 2010/0041604 A1
RECORD: Rec_0062171 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-Influenza
Influenza virus
PaperNovel Antiviral Peptides Against Influenza Virus Evidence URLhttps://patents.google.com/patent/US20100041604/en PatentUS 20100041604
RECORD: Rec_0132040 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0303286 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); MDCK
0 %
Hemagglutinin assay
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/