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MYP_072863
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Basic Information
[Pro]8-VmCT1-NH2 (Derived from VmCT1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C72H104N16O16
Standard
Sequence
FLGALWNPAKSVF
Physicochemical Analysis
1449.69 Da
8.75
0.76
0.55
0.0584
0.76
0.41
0.44
43.01
97.69
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
508.86
-1.65
17.0
17.0
42.0
104.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0137680 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
100
Hemolysis
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0142755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli SBS 363
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0144900 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus megaterium ATCC 10778
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0167045 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Serratia marcescens ATCC 4112
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0204206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Micrococcus luteus A270
12.5 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
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