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MYP_072787
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Basic Information
Cecropin-A (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
35 amino acids
C179H305N53O44
Standard
Sequence
RWKVFKKIEKVGRNIRDGVIKAAPAIEVLGQAKAL
Physicochemical Analysis
3903.67 Da
10.64
5.76
5.54
0.1646
-0.11
0.91
-0.06
61.85
114.29
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1599.62
-10.84
56.0
50.0
137.0
276.0
4.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317374 VERIFIED: NO
Provenance & Taxonomy
Heliothis virescens [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram Negative Bacteria and Gram Positive Bacteria
RECORD: Rec_0349868 VERIFIED: NO
Provenance & Taxonomy
Heliothis virescens [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Lytic
RECORD: Rec_0355499 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
Cecropin
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID9712710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9712710/
RECORD: Rec_0361220 VERIFIED: YES
Provenance & Taxonomy
Heliothis virescens [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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