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MYP_072763
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Basic Information
RFR-ChBac3.4-1-NH2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C193H289N61O32
Standard
Sequence
RFRRFRLPFRRIHPPPFVRIHPPPFYRRFL
Physicochemical Analysis
3975.75 Da
12.00
8.93
8.63
0.2978
-0.73
0.87
-0.31
129.84
61.67
0.2333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1480.38
-5.45
54.0
43.0
115.0
286.0
16.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human myelogenous leukemia K562
20
IC50
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0359423 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: K562
20±3.4 μM
IC50
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0361352 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human PBMC (50% Cytotoxicity at 18.3+-4.1 microM
4.1 μM
Hemolysis
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0377974 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii 7226/16
8 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0383207 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa 522/17
16 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
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