Peptide Database

Peptide NameCcl21b

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC631H1041N191O183S11

DescriptionStandard

        MAQMMTLSLLSLVLALCIPWTQGSDGGGQDCCLKYSQKKIPYSIVRGYRKQEPSLGCPIPAILFLPRKHSKPELCANPEEGWVQNLMRRLDQPPAPGKQSPGCRKNRGTSKSGKKGKGSKGCKRTEQTQPSRG
    

Molecular Weight14583.90 Da

Isoelectric Point (pI)9.92

Net Charge (pH 7.0)14.52

Net Charge (pH 7.4) 14.11

Charge Density (pH 7.0) 0.1092

GRAVY Index-0.72

Hydrophobic Moment 0.74

Boman Index-0.15

Instability Index46.81

Aliphatic Index 63.08

Aromaticity 0.0451

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6035.06

LogP -69.62

H-bond Donors 213.0

H-bond Acceptors 210.0

Rotatable Bonds 490.0

Heavy Atoms 1016.0

Ring Count 22.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022827 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetCCR7 (Human); CCR7 (Mouse)

Activity4.7 nM

MethodIC50