Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC301H457N71O76S7

DescriptionStandard

        FLGFCFVIIIFFILSEFDIYKICGYGTARCRSRCKAEEFQIGACPDAYPCCLKKPTL
    

Molecular Weight6510.73 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 1.37

Charge Density (pH 7.0) 0.0297

GRAVY Index0.56

Hydrophobic Moment 0.35

Boman Index0.21

Instability Index39.28

Aliphatic Index 87.37

Aromaticity 0.1754

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2327.53

LogP -13.25

H-bond Donors 88.0

H-bond Acceptors 85.0

Rotatable Bonds 208.0

Heavy Atoms 455.0

Ring Count 13.0

Amide Bonds 57.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0173087 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence