Peptide Database

Peptide NamePreprohepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC451H707N133O139S12

DescriptionStandard

        MKWAHVALAAAVVIACICILQTAAVPFAQQEQDEHQMEIETPQQNEHSTETTETSQGQTNPLAFFRTKRQSHLSLCRYCCNCCRNKGCGYCCKF
    

Molecular Weight10601.03 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0025

GRAVY Index-0.32

Hydrophobic Moment 0.66

Boman Index-0.03

Instability Index54.44

Aliphatic Index 60.32

Aromaticity 0.0745

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4410.32

LogP -51.34

H-bond Donors 159.0

H-bond Acceptors 155.0

Rotatable Bonds 349.0

Heavy Atoms 735.0

Ring Count 15.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298314 VERIFIED: YES

Provenance & Taxonomy

OrganismMegalobrama amblycephala [Animal]

FamilyHepcidin

Tax ID75352

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal