Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length443 amino acids

Chemical FormulaC2221H3502N586O609S18

DescriptionStandard

        MARGPDNAPRWALLAVLAAVGTAMTAAINPGAVARISQKGLDYACQEGTAVLQKDLEKIKIPNYSRKFKIKVLGKGNYSFYSMNVRGFQLPSRQVILVPDVGLKLFIGNASVKISGKWKAQKSFMWLIRLFRKQIESSIRNNIQDKICKVVANSVSSKLQPFFQNLPVMAKIDAVAGIDYRLVAPPTATSEYLDGHLKGEFFSWADPMPPPFAPPALEFPAIHDRMVYLGLSEYFFNTAGLVYYEAGALQLTLTDDMIPEKSSFRLTTRFFGTFLPQVAQMFPDMNMQLDVSVSTPPHLSMQSSGLVLTPYLEAETFAILPNSSLASLFLLGLSTNASVRVGAMASRLVGELELDRLLLELKHSNIGPFPVALLQAIMDYAVPTLVLPRVNQKLQRGFPLPVPSHFQLYNPVLRSHQGVLLFGADVRHAEVAPSAGGCRRSCS
    

Molecular Weight48734.29 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)12.10

Net Charge (pH 7.4) 11.38

Charge Density (pH 7.0) 0.0273

GRAVY Index0.12

Hydrophobic Moment 0.76

Boman Index0.13

Instability Index40.70

Aliphatic Index 97.77

Aromaticity 0.0948

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225590 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus (Gray mouse lemur) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria