Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length469 amino acids

Chemical FormulaC2461H3910N628O687S13

DescriptionStandard

        MRFWWVFVLLSLFLFQLEANPEVRIRITQRGLNYAKEIGMKLFEQELRTRIFPDETGTEKYLFGIIDYTVSRIQITSISIYNSSVVLIPGNGIRLLIKNISVTVTTRWTLNNWLIDYQGEVDISIFELSITTNMIVTQNNRGDLLVSVQNCQLSMGNIEVQLNSEGRWYYNGFVQHLEKVIRTRLESQLCLNVILRIQKETEVLKELKGVFQINPLIQVKYSLITPPEVFKSYVDLDFKVSVYFSRNHTESPFVAAPFTLPEKNNYMLFSGISESLLNSITLTYYTTRVSKVTFSEEHSSYFNLTTDTLSRVIPQVMQHYTKSHPVRMKLMVTAAPVLRLQNNSFTIEIPCFVVVSALLSNSMIKPIFAVNASIGLKANAVIAKQKLIVLPQLQRLYLSLTYSSIGSFQVQRLKNFLSYSLQNTVIPPIAAALKRGLQLPTMAKLFLSEAVTEVKKGYILISTDLNYKY
    

Molecular Weight53704.01 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)12.94

Net Charge (pH 7.4) 12.31

Charge Density (pH 7.0) 0.0276

GRAVY Index0.13

Hydrophobic Moment 0.78

Boman Index0.12

Instability Index30.24

Aliphatic Index 111.30

Aromaticity 0.1066

Extinction Coeff. Reduced 58790.00

Extinction Coeff. Oxidized 58915.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410572 VERIFIED: NO

Provenance & Taxonomy

OrganismNotechis scutatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria