MYP_072613
stLRL
Antimicrobial
Antimicrobial
▸
Antibacterial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
Venom / Toxin
▸
General toxin
▸
Cytotoxicity
Standard
7 amino acids
C36H69N13O8
Standard
LALRLAR
812.02 Da
12.00
1.76
1.56
0.2514
0.86
0.82
-0.09
36.09
195.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
361.72
-1.99
14.0
10.0
27.0
57.0
0.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0040524
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S-(2,4)-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antimicrobial
Antibacterial
Pseudomonas aeruginosa PAO1
32.00 μM
MIC
RECORD: Rec_0128679
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S-(2,4)-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli K99
16.00 μM
MIC
RECORD: Rec_0148244
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S-(2,4)-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli ATCC 25922
16.00 μM
MIC
RECORD: Rec_0172213
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S-(2,4)-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli 987P
8.00 μM
MIC
RECORD: Rec_0196390
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S-(2,4)-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli UB1005
16.00 μM
MIC
Showing 5 records on this page · Page 1 of 2