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MYP_072556
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Basic Information
CP26
Anticancer ▸ Anti-proliferative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C134H230N34O34
Standard
Sequence
KWKSFIKKLTSAAKKVVTTAKPLISS
Physicochemical Analysis
2861.47 Da
10.78
6.75
6.54
0.2597
-0.07
0.69
-0.01
1.06
93.85
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1121.57
-9.44
41.0
41.0
99.0
202.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003709 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
greater, Staphylococcus epidermidis
32 μg/mL
MIC
PaperSalt-resistant alpha-helical cationic antimicrobial peptides.
RECORD: Rec_0007662 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
CP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei 427 (procyclic form)
17.5 μM
IC50; Alamar Blue assay
PaperAntimicrobial peptide killing of African trypanosomes PMID21517904 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21517904/
RECORD: Rec_0026414 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US20030096949A1/en PatentUS 2003/0096949 A1
RECORD: Rec_0055623 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella typhimurium
3 μg/mL
MIC
PaperBiological properties of structurally related alpha-helical cationic antimicrobial peptides. Infect Immun. 1999 Apr;67(4):2005-2009. doi: 10.1128/IAI.67.4.2005-2009.1999. PMID: 10085049. PMID10085049 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10085049/
RECORD: Rec_0070268 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes NCTC 7973
16 μg/mL
MIC
PaperSalt-resistant alpha-helical cationic antimicrobial peptides.
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