Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length469 amino acids

Chemical FormulaC2453H3908N626O678S13

DescriptionStandard

        MRFWWVFILLSLFLFQLEANPEVRIRITQRGLNYAKEIGMKLLEQELRTRIFPDEIGTEKYFFGKVDYTVSRIQIMSTSIYNSSVVLIPGNSIGLLIKNISVTVTTHWTLNNWLIDYQGEVEISILGLSITTNMIVAQNNRGDFLVSVENCQLTTGNIEVQLNSEGRWFYNAFVQRLEKVIRTRLENQLCLNVILRIQKETKVLKGLKGVFQINPFIQVKYSLIKPPEVFKSYVDLDFKVSVYFSSNHTESPFVAAPITLPEKNNYMLFGGISESLLNSITLTYYTTRVSKITFLEEHSSNFNLTTDTLSRVIPQVIQHYAKSHPVRMKLMVTAAPVLRLQNNSFTIEIPCFVVVSALLSNSMIKPIFAMNASIGLKAKAVIAKQKLIVLLQLQRLYLSLTYSSIGSFQVQRLKNFLSYSLQNTVIPPIAAALKRGLQLPTMAKLVFSEAVTEVNKGYILISTDLNYKY
    

Molecular Weight53433.90 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)15.94

Net Charge (pH 7.4) 15.31

Charge Density (pH 7.0) 0.0340

GRAVY Index0.17

Hydrophobic Moment 0.81

Boman Index0.13

Instability Index31.43

Aliphatic Index 112.99

Aromaticity 0.1045

Extinction Coeff. Reduced 55810.00

Extinction Coeff. Oxidized 55935.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052735 VERIFIED: NO

Provenance & Taxonomy

OrganismPantherophis guttatus (Corn snake) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria