Peptide Database

Peptide NamePhylloseptin-Az4 (PLS-Az4) (Phylloseptin-12) (PS-12)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC278H458N70O98S

DescriptionStandard

        LVLFLGLVSLSICEEEKRETEEEENDQEEDDKSEEKRFLSLLPSIVSGAVSLAKKLG
    

Molecular Weight6381.09 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-8.22

Net Charge (pH 7.4) -8.46

Charge Density (pH 7.0) -0.1442

GRAVY Index-0.38

Hydrophobic Moment 0.63

Boman Index-0.07

Instability Index75.61

Aliphatic Index 105.96

Aromaticity 0.0351

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2745.55

LogP -25.98

H-bond Donors 94.0

H-bond Acceptors 91.0

Rotatable Bonds 228.0

Heavy Atoms 447.0

Ring Count 3.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234686 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus azureus [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Non-hemolytic

TargetNo Target Organism Found