Peptide Database

Peptide NameEsculentin-2-ALb (Amolopin-9b)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC367H605N99O108S5

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCEEERSADEDDGEKGVKRGIFSLIKTAAKFVGKNLLKQAGKAGVEHLACKANNQC
    

Molecular Weight8292.65 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)2.57

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0338

GRAVY Index-0.04

Hydrophobic Moment 0.71

Boman Index0.03

Instability Index24.43

Aliphatic Index 92.50

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3371.49

LogP -31.90

H-bond Donors 119.0

H-bond Acceptors 117.0

Rotatable Bonds 295.0

Heavy Atoms 579.0

Ring Count 6.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348790 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyFrog skin active peptide (FSAP); Esculentin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0364248 VERIFIED: YES