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MYP_072491
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Basic Information
Esculentin-2-ALb (Amolopin-9b)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
76 amino acids
C367H605N99O108S5
Standard
Sequence
MFTMKKSLLLLFFLGTISLSLCEEERSADEDDGEKGVKRGIFSLIKTAAKFVGKNLLKQAGKAGVEHLACKANNQC
Physicochemical Analysis
8292.65 Da
8.88
2.57
2.23
0.0338
-0.04
0.71
0.03
24.43
92.50
0.0658
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3371.49
-31.90
119.0
117.0
295.0
579.0
6.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0067439 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
B. cereus (Gram-positive)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0130777 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Candida albicans
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0174242 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
B. pumilus (Gram-positive)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0255757 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperFive novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis. Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan;155(1):72-76. doi: 10.1016/j.cbpb.2009.10.003. PMID: 19843479. PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0314001 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Escherichia coli (Gram-negative)
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
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