MYP_072486
EeCentrocin 2
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Standard
32 amino acids
C156H246N52O38S
Standard
WGHKLRSSWNKVKHAVKKGAGYASGACRVLGH
3490.01 Da
10.67
7.01
6.63
0.2189
-0.60
0.61
-0.08
54.28
64.06
0.0938
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1460.95
-15.03
55.0
49.0
116.0
247.0
8.0
32.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0418451
VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamylation
Amidation
Chain A (shown) is connected with chain B (EVGKYCAVAHAIH, amidated) via a disulfide bond. In chain B, the N-terminal Q is pyroglutamic acid (Glp). Trp is bromated at position 6 (6-bromotryptophan). Sequence analysis: APD analysis reveals that the sequence of chain A shows 46.8% similarity to EeCentrocin 1
Bio-Activity Profile
Antimicrobial
Antifungal
Staphylococcus epidermidis
3.13 μM
MIC
RECORD: Rec_0427356
VERIFIED: YES
Provenance & Taxonomy
Echinus esculentus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Escherichia coli ATCC 25922
1.56 μM
MIC
Showing 2 records on this page · Page 6 of 6