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MYP_072446
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Basic Information
Temporin-1DRa [Aib4]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HFLXTLVNLAKKIL
Physicochemical Analysis
0.00 Da
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0270364 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 4
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 900280
8 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0271212 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0339934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Mouse fibroblasts L929
9 μM
LC50
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0339967 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 4
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25726
64 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
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