‹ ›
MYP_072446
← PREVIOUS NEXT → BACK
Basic Information
Temporin-1DRa [Aib4]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HFLXTLVNLAKKIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0013656 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 4
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
2 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0066269 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
25 μM
LC50
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0176402 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0181983 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 4
Bio-Activity Profile
Hemolytic
human red blood cells
25 μM
HC50
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0240896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 4
Bio-Activity Profile
Anticancer Cytotoxic
Human hepatocellular carcinoma HepG2
25 μM
LC50
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2