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MYP_072442
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Basic Information
P124, GBV-C E2 (370-387)
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
18 amino acids
C84H135N21O23
Standard
Sequence
WVNQLAVLGLPAVDAAVA
Physicochemical Analysis
1807.10 Da
4.05
-1.24
-1.44
-0.0688
1.32
0.24
0.53
13.59
157.22
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
688.50
-4.02
22.0
22.0
53.0
128.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID20718496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718496/
RECORD: Rec_0087984 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID20718496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718496/
RECORD: Rec_0113577 VERIFIED: YES
Provenance & Taxonomy
GB virus C [Virus]
54290
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
CEM-174
Qualitative inhibition
PaperEffect of synthetic peptides belonging to E2 envelope protein of GB virus C on human immunodeficiency virus type 1 infection. PMID20718496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718496/
RECORD: Rec_0128846 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibition of gp41-induced cell-cell fusion in CEM-174 cells
332.7 μM
IC50
PMID20718496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718496/
RECORD: Rec_0136781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of HIV(BAL) infection in TZM-bl Cells
94.7 μM
IC50
PMID20718496 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718496/
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