Peptide Database

Peptide NameBeta-defensin 39

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC364H598N102O101S9

DescriptionStandard

        MKISCFLLLVLSLSCFQINSVSGIDSVKCFQKNNTCHTIRCPYFQDEVGTCYEGRGKCCQKRLLSIRVPKKKV
    

Molecular Weight8307.85 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)7.51

Net Charge (pH 7.4) 7.10

Charge Density (pH 7.0) 0.1028

GRAVY Index0.02

Hydrophobic Moment 0.48

Boman Index-0.02

Instability Index25.48

Aliphatic Index 87.95

Aromaticity 0.0822

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3318.97

LogP -33.10

H-bond Donors 124.0

H-bond Acceptors 119.0

Rotatable Bonds 284.0

Heavy Atoms 576.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155644 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZF7/entry; https://bblserver.org.in/ampdb/