Peptide Database

Peptide NameFLRFamide II

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC39H57N11O10

DescriptionStandard

        GNSFLRF
    

Molecular Weight839.94 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.1086

GRAVY Index0.03

Hydrophobic Moment 0.73

Boman Index0.06

Instability Index23.96

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 363.14

LogP -3.40

H-bond Donors 13.0

H-bond Acceptors 11.0

Rotatable Bonds 26.0

Heavy Atoms 60.0

Ring Count 2.0

Amide Bonds 7.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0424005 VERIFIED: YES

Provenance & Taxonomy

OrganismManduca sexta [Animal]

FamilyFMRFamide-like peptide

Tax ID7130.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

GPCR agonist RFamide

TargetCHO cell membrane expressing Caenorhabditis elegans FLP15-R (C10C6.2)

Activity4.811 μM

MethodEC50

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2