Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length469 amino acids

Chemical FormulaC2312H3727N613O648S23

DescriptionStandard

        MHLWCWLALVAFIPVTSSTSPGVKVKITEKGLEYGKIGMVTLQQKLKAIKVPDISGTQKVAPIGKVRYSLSKMQIMNLGLPKSALTLAPGTGVSLSISNAFINLHGNWKVKYMNFIKDSGSFDLSVNGLTITTSISVKSDETGRPVVNSVNCGATVGSAKIKFHGGARSMWNKRPHIVHVCSNMLQICPLVADAISELNPHLKTLNVLAKVDKLAEIEYSMVSSPVISKSSIDLSLKGEFYNIGQHQEPPFSPKPFPMPPQVNNMLYIGVSTFTINSAAFVYNKAGALSLFITDDMIPPSSPIRLNTRTFGAFIPQIAKRFPGLMMKLLVKTVKDPGITLEGNNVTVQTTSTVTAYAIQPNSTLTPLFILNVDISVSARMYLTEMRLAGAVALNTMDMNLRTSYVGDFQVRPLQNIFQIVLKVAVIPRVNGELAMYFHAFTCSTVSTRRIYVHKVAQAAKRPRSPVLQS
    

Molecular Weight51216.54 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)24.24

Net Charge (pH 7.4) 23.40

Charge Density (pH 7.0) 0.0517

GRAVY Index0.15

Hydrophobic Moment 0.73

Boman Index0.14

Instability Index38.49

Aliphatic Index 98.89

Aromaticity 0.0746

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090914 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria