MYP_072372
Piscidin 4
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antiparasitic
▸
General antiparasitic
▸
Antiparasitic
Standard
44 amino acids
C235H360N80O63
Standard
FFRHLFRGAKAIFRGARQGWRAHKVVSRYRNRDVPETDNNQEEP
5313.87 Da
11.23
4.94
4.63
0.1123
-1.23
0.93
-0.38
39.54
46.59
0.1364
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
2380.07
-24.70
85.0
70.0
175.0
378.0
11.0
48.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0013385
VERIFIED: YES
Provenance & Taxonomy
Hybrid striped [Animal]; Actinopterygii [Animal]
Piscidin
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0031961
VERIFIED: YES
Provenance & Taxonomy
Morone chrysops x Morone saxatilis [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
RECORD: Rec_0086773
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 70.5%, E 0.0%, T 9.1%, C 20.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
Antimicrobial
RECORD: Rec_0113314
VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
The native peptide has a modified amino acid at position 20 that, based upon mass spectrometry data, is probably a hydroxylated tryptophan. SAR: Synthetic piscidin 4 (with an unmodified tryptophan at position 20) has similar antibacterial activity to that of the native peptide
Bio-Activity Profile
Antimicrobial
Antiparasitic
Staphylococcus aureus
1.18 μM
MIC
RECORD: Rec_0137900
VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
The native peptide has a modified amino acid at position 20 that, based upon mass spectrometry data, is probably a hydroxylated tryptophan. SAR: Synthetic piscidin 4 (with an unmodified tryptophan at position 20) has similar antibacterial activity to that of the native peptide
Bio-Activity Profile
Antimicrobial
Antiparasitic
Escherichia coli
9.41 μM
MIC
Showing 5 records on this page · Page 1 of 3