Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC981H1548N264O264S9

DescriptionStandard

        PTPPPVAHEPMLLVAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELQLWARQQPLLSCHPDALHGALFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRSRLGGTVRLTGLVPDPDLAWTPLPALCQAQVLPVPQVKHLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight21552.98 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)4.28

Net Charge (pH 7.4) 3.92

Charge Density (pH 7.0) 0.0218

GRAVY Index0.08

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index58.37

Aliphatic Index 95.05

Aromaticity 0.0765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8227.95

LogP -99.54

H-bond Donors 280.0

H-bond Acceptors 281.0

Rotatable Bonds 666.0

Heavy Atoms 1518.0

Ring Count 47.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156258 VERIFIED: NO

Provenance & Taxonomy

OrganismChloropsis cyanopogon [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria