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MYP_072365
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Basic Information
Ixosin (4-18)[E8K,E13L,S16V], Ixosin-pch4-18
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C86H147N25O19S
Standard
Sequence
KVMRKVLGYLRNVYK
Physicochemical Analysis
1867.31 Da
10.56
4.76
4.54
0.3170
-0.34
0.76
-0.22
3.37
110.00
0.1333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
756.13
-3.68
28.0
25.0
65.0
131.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0236603 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0319162 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa[10-20% Killing = 2 microM
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0344644 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa (19% Killing=2 μM)
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0399723 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
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