Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC926H1409N209O283S9

DescriptionStandard

        QIDDLAEVDYSLSSSPAVFRPFIDLDLKGVVFPAGNYAGSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFSINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPIISLQQDSFMLEIQGSMEVLAILPDSTTQPLFTLNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20285.91 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.51

Charge Density (pH 7.0) -0.0719

GRAVY Index0.32

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index49.43

Aliphatic Index 94.40

Aromaticity 0.1304

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7785.21

LogP -84.90

H-bond Donors 265.0

H-bond Acceptors 279.0

Rotatable Bonds 648.0

Heavy Atoms 1427.0

Ring Count 35.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187955 VERIFIED: NO

Provenance & Taxonomy

OrganismNicator chloris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria