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MYP_072335
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Basic Information
Cecropin(1-7)+Melittin(2-9) K6,7(Me 3 )
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKLFXXIGAVLKVL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019956 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania mexicana pifanoi MHOM/VE/60/Ltrod
27.0
LC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0063616 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Acinetobacter baumannii ATCC 19606
2.6
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0169141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania mexicana pifanoi MHOM/VE/60/Ltrod
9.2
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0219676 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,7
Bio-Activity Profile
Hemolytic
sheep red blood cells
8.8 μM
Hemolysis
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0331919 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Staphylococcus aureus CECT 240
10.7
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
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