Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC349H548N112O100S9

DescriptionStandard

        MTGLRGRHHTLRCMGNTGVCRPSCRRTEHPYLYCLNYQPCCLQSYMRISIAGREEKDDWSQENRWPKIP
    

Molecular Weight8201.36 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0683

GRAVY Index-0.92

Hydrophobic Moment 0.48

Boman Index-0.25

Instability Index75.79

Aliphatic Index 50.87

Aromaticity 0.0870

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3450.03

LogP -36.97

H-bond Donors 129.0

H-bond Acceptors 117.0

Rotatable Bonds 265.0

Heavy Atoms 570.0

Ring Count 16.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409860 VERIFIED: NO

Provenance & Taxonomy

OrganismEnhydra lutris kenyoni [Bacterium]

FamilyDefensin

Tax ID391180

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence