Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length167 amino acids

Chemical FormulaC815H1289N245O246S9

DescriptionStandard

        MMYRSASSNRRKEQSSMAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQSLRSLLVELKVQYSGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight18744.03 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.01

Net Charge (pH 7.4) 4.41

Charge Density (pH 7.0) 0.0300

GRAVY Index-0.54

Hydrophobic Moment 0.75

Boman Index-0.10

Instability Index51.19

Aliphatic Index 68.26

Aromaticity 0.0778

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7986.98

LogP -88.89

H-bond Donors 284.0

H-bond Acceptors 266.0

Rotatable Bonds 632.0

Heavy Atoms 1315.0

Ring Count 27.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250753 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage KP32_isolate 192 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic