Peptide Database

Peptide NamePepsin

Function Ontology

Anticancer

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length385 amino acids

Chemical FormulaC1845H2824N450O598S12

DescriptionStandard

        MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA
    

Molecular Weight41261.59 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-30.26

Net Charge (pH 7.4) -30.82

Charge Density (pH 7.0) -0.0786

GRAVY Index0.07

Hydrophobic Moment 0.73

Boman Index0.19

Instability Index40.80

Aliphatic Index 91.38

Aromaticity 0.1013

Extinction Coeff. Reduced 58330.00

Extinction Coeff. Oxidized 58705.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0100827 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Bos taurus [Animal]; Ovis aries [Animal]

FamilyImmunoglobulin

Tax ID9606;9913;9940

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory Hormone replacement Enzyme replacement