Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length464 amino acids

Chemical FormulaC2295H3643N613O650S18

DescriptionStandard

        MGVQSLAVACGALALCLALTTATNPGFMVRITQAGLDYANQHGIAILEKELAQLKMPDISGDSRVLRVGKVHYELSRLRLRDFHLPYSRITPISNMGLQVSISNAFAELDGDWRVKVFFVRDHGSFNLKVENIYIKIILRLGSDTNGKPTISTADCSARISKVRVLFSGKFGWLYNLFHSAIESKLRKNLESKVCDNVVKSVHNDLQTYIQTLPVTARIDDKTGIDYSLVAPPKATTQSLDLALKGEFYSLGHRSTVPFSPLPLAFPSDHEHMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKDVGFRLDTSVFSAFIPQLEEMYPNMAMKFRLSAPTAPFLTIGPGGISFQPTVDAQAYAILPNSTLAPLFLLSLTGNVSAVINVRSGRIVGSLDVGRIRLSLKDSTVGTFQVRMMQSLMNIMTSSTLLPRLNGENLLGGMGVLQHPPFTLLLQVAPAH
    

Molecular Weight50799.36 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 7.57

Charge Density (pH 7.0) 0.0184

GRAVY Index0.16

Hydrophobic Moment 0.66

Boman Index0.14

Instability Index36.02

Aliphatic Index 100.67

Aromaticity 0.0862

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012135 VERIFIED: NO

Provenance & Taxonomy

OrganismCyanoderma ruficeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria