Peptide Database

Peptide NameEsculentin-2-AJ6 antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC367H590N92O111S6

DescriptionStandard

        MFTMKKSLLVLFFLGIISLFFCEEERNADEDDGEMTEEEKRGILSTLKQFGKAAVKGVAQSFLNTASCKLAKTC
    

Molecular Weight8259.55 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0204

GRAVY Index0.02

Hydrophobic Moment 0.66

Boman Index0.06

Instability Index41.76

Aliphatic Index 83.11

Aromaticity 0.0946

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3304.54

LogP -29.62

H-bond Donors 117.0

H-bond Acceptors 116.0

Rotatable Bonds 290.0

Heavy Atoms 576.0

Ring Count 7.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173134 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyEsculentin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0319306 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

FamilyBrevinin

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal