Peptide Database

Peptide Namehuman GIP(5-30)NH2

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC143H215N35O41S

DescriptionStandard

        TFISDYSIAMDKIHQQDFVNWLLAQK
    

Molecular Weight3112.51 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.76

Charge Density (pH 7.0) -0.0582

GRAVY Index-0.14

Hydrophobic Moment 0.35

Boman Index0.11

Instability Index25.25

Aliphatic Index 93.85

Aromaticity 0.1538

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1252.51

LogP -8.96

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 103.0

Heavy Atoms 220.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354629 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-Termamidated

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Receptor antagonist Antidiabetic Hormonal activity

TargetGIP receptor (Human)

Activity5.9 nM

MethodKi