Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length481 amino acids

Chemical FormulaC2421H3800N640O673S15

DescriptionStandard

        MGAQSLAAACGALALCLALTGATNPGFMVRITQSGLDYAHQQGIAILEKELAQLKLPDISGDFRIQHVGKVHYEISRLDLRSFSLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKIYFIRDHGSFDLKVENVYIKINLKLGSNASGKPTIDTSDCSTRISKVRVHFWGKFGWLYNLFYGAVESRFRNILERKVCENVVTSVRSELQPYLQTLPVTARIDDKAGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSTVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSVIPKSMGFHLNTSTFSAFIPQLEKMYPDMPMKLRLSAPSAPFLNIGPGGLLLKPVVDIQAYAILPSSSLAPLFLLSLTSNVSAVIDVKLGHIVGSLNMGRLRLSLKHSDVGTFQVRMLQSIMNTIASSMLLPQLNERLAEGFPLPLPDRIQLSNILVRFHQNFLLLGADVRYQPLEWR
    

Molecular Weight53120.93 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 5.57

Charge Density (pH 7.0) 0.0136

GRAVY Index0.15

Hydrophobic Moment 0.72

Boman Index0.14

Instability Index36.00

Aliphatic Index 103.20

Aromaticity 0.0977

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245206 VERIFIED: NO

Provenance & Taxonomy

OrganismAquila chrysaetos chrysaetos [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria