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MYP_072069
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
10 amino acids
C60H94N14O15
Standard
Sequence
YIPIQYVLSR
Physicochemical Analysis
1251.47 Da
8.59
0.76
0.55
0.0758
0.40
0.32
0.20
17.84
146.00
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
482.11
-1.52
17.0
16.0
37.0
89.0
3.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211119 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
174.5 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0220124 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Casoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Antagonist
opioid receptor
50.0
PaperChiba H., Tani F., Yoshikawa M.. Opioid antagonist peptides derived from kappa-casein. J. Dairy Res. 56, 363-366, 1989.
RECORD: Rec_0310035 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Opioid antagonist
PaperContents of agonistic and antagonistic opioid peptides in different cheese varieties | Sienkiewicz-Szłapka, E. et al. | DOI: 10.1016/j.idairyj.2008.10.011 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0361474 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casoxin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
40 μM
PaperIdentification of Casoxin C, An Ileum-contracting Peptide Derived From Bovine kappa-casein, as an Agonist for C3a Receptors | Takahashi, M. et al. | DOI: 10.1016/s0196-9781(97)00044-2 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0365568 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 30.0%, C 70.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
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