Peptide Database

Peptide NameKassorin-S (PreproKassorin-S)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC373H618N106O128S3

DescriptionStandard

        MLTLKKSMLLLFFLGMVSLSLANSKRADEEGEDKRADEEGEDKRADEEGEDKRADEEGEEKRKRFLGGILNTITGLLG
    

Molecular Weight8731.73 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-6.46

Net Charge (pH 7.4) -6.72

Charge Density (pH 7.0) -0.0829

GRAVY Index-0.80

Hydrophobic Moment 0.64

Boman Index-0.21

Instability Index51.47

Aliphatic Index 80.13

Aromaticity 0.0385

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3857.37

LogP -39.16

H-bond Donors 134.0

H-bond Acceptors 125.0

Rotatable Bonds 319.0

Heavy Atoms 610.0

Ring Count 3.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152550 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0241467 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans

RECORD: Rec_0271306 VERIFIED: YES

Provenance & Taxonomy

OrganismKassina senegalensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)