Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC636H1026N178O205S3

DescriptionStandard

        MNAKTSFRTATRVVAAAGLAAGLALAVQPAAVAAPSAPVVAVSPASALADGQQVSVTASGLTPNTVFHLGQCAFVEPGKYGCNAETGKDITSDASGKINTTFTVRSSFTAVVTADGAVWGTVDAKKIQTQVGLGSGTGEGGGQVVSFK
    

Molecular Weight14542.21 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.26

Charge Density (pH 7.0) 0.0106

GRAVY Index0.27

Hydrophobic Moment 0.73

Boman Index0.20

Instability Index15.27

Aliphatic Index 81.15

Aromaticity 0.0541

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6059.65

LogP -81.76

H-bond Donors 211.0

H-bond Acceptors 211.0

Rotatable Bonds 467.0

Heavy Atoms 1022.0

Ring Count 16.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095580 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. ST5x [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal