Peptide Database

Peptide NameNRC-126

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC134H211N39O30

DescriptionStandard

        GWRKWIKKATHVGKHIGKAALDAYI
    

Molecular Weight2848.35 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.62

Charge Density (pH 7.0) 0.1972

GRAVY Index-0.41

Hydrophobic Moment 0.70

Boman Index0.01

Instability Index18.53

Aliphatic Index 90.00

Aromaticity 0.1200

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1120.42

LogP -6.06

H-bond Donors 41.0

H-bond Acceptors 37.0

Rotatable Bonds 95.0

Heavy Atoms 203.0

Ring Count 7.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403278 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes

Activity>256 μg/mL

MethodHemolysis

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