Peptide Database

Peptide Namealpha-Conotoxin SII

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC66H101N21O26S6

DescriptionStandard

        GCCCNPACGPNYGCGTSCS
    

Molecular Weight1797.02 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0158

GRAVY Index0.07

Hydrophobic Moment 0.10

Boman Index0.15

Instability Index49.44

Aliphatic Index 5.26

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 736.64

LogP -14.67

H-bond Donors 30.0

H-bond Acceptors 32.0

Rotatable Bonds 50.0

Heavy Atoms 119.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128297 VERIFIED: NO

Provenance & Taxonomy

OrganismConus striatus [Animal] [Animal]; Conus striolatus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-18, 3-8, 4-14

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0205678 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 15.8%, T 36.8%, C 47.4% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic