Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC502H804N142O152S10

DescriptionStandard

        VPIMKPCLMSIAIFLILVQKTPGGLFRSHNDKSQEPWNPCELYQGMCRNNCRKSEIQYLNCLHDQKCCLKFSAKKVTSSINVKEDYNSSSNVSVANTSSHSPV
    

Molecular Weight11581.26 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.0479

GRAVY Index-0.36

Hydrophobic Moment 0.53

Boman Index-0.04

Instability Index50.06

Aliphatic Index 75.63

Aromaticity 0.0680

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4769.45

LogP -54.89

H-bond Donors 168.0

H-bond Acceptors 170.0

Rotatable Bonds 386.0

Heavy Atoms 806.0

Ring Count 17.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314593 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence