Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC461H733N127O141S7

DescriptionStandard

        MKTFVLLSALVLLAYQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
    

Molecular Weight10534.97 Da

Isoelectric Point (pI)5.65

Net Charge (pH 7.0)-2.36

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0254

GRAVY Index-0.17

Hydrophobic Moment 0.63

Boman Index-0.02

Instability Index45.31

Aliphatic Index 82.80

Aromaticity 0.0860

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4351.55

LogP -43.29

H-bond Donors 157.0

H-bond Acceptors 148.0

Rotatable Bonds 357.0

Heavy Atoms 736.0

Ring Count 12.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394411 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence