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MYP_071872
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Basic Information
Temporin-1CSb
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C69H118N14O15
Standard
Sequence
FLPIIGKLLSGLL
Physicochemical Analysis
1383.76 Da
8.75
0.76
0.55
0.0584
1.82
0.47
0.67
10.98
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
0.67
15.0
16.0
45.0
98.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187129 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20080170991A1/en PatentUS 2008/0170991 A1
RECORD: Rec_0199794 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0240303 VERIFIED: YES
Provenance & Taxonomy
Rana cascadae [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Gram-negative Escherichia coli ATCC 25922
2.5 μM
MIC
PaperPeptide defenses of the cascades frog Rana cascadae: implications for the evolutionary history of frogs of the Amerana species group
RECORD: Rec_0243300 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
VCT
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperToxicon. 2013 Nov;74:151-7. | http://www.ncbi.nlm.nih.gov/pubmed/24012601 PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0243880 VERIFIED: YES
Provenance & Taxonomy
Rana cascadae [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Klebsiella pneumoniae IS 59#
40 μM
MIC
PaperPeptide defenses of the cascades frog Rana cascadae: implications for the evolutionary history of frogs of the Amerana species group
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