Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC480H769N121O131S7

DescriptionStandard

        MKLFLVLIVLLSQVLTAGAKPPRCFHNVAGYCKKKCKLGEISEIGCLHGKLCCVNEEENKKYYKFQQPPPHSDQKVEGVSDYIIYPTITLVSVL
    

Molecular Weight10555.43 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0394

GRAVY Index0.03

Hydrophobic Moment 0.58

Boman Index0.10

Instability Index32.64

Aliphatic Index 101.49

Aromaticity 0.0851

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4014.06

LogP -29.63

H-bond Donors 140.0

H-bond Acceptors 145.0

Rotatable Bonds 351.0

Heavy Atoms 739.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104280 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Tax ID885580

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic