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MYP_071740
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Basic Information
Der-PS4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
28 amino acids
C132H222N38O36S
Standard
Sequence
ALWKTLLKHVGKAAGKAALNAVTDMVNQ
Physicochemical Analysis
2949.47 Da
10.00
2.88
2.63
0.1029
0.16
0.65
0.14
0.25
108.21
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1204.60
-10.77
41.0
41.0
100.0
207.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0265082 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus ATCC 12600 MRSA ATCC BAA-1720
4-8 μM
MIC
PaperEvaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of Phyllomedusa sauvagii.
RECORD: Rec_0273799 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Candida albicans
4 μM
MIC
PMID31426323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31426323/
RECORD: Rec_0301631 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans ATCC 10231
4 μM
MIC
PaperEvaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of Phyllomedusa sauvagii.
RECORD: Rec_0306380 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
8 μM
MIC
PMID31426323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31426323/
RECORD: Rec_0362418 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Candida albicans
16 μM
MBC
PMID31426323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31426323/
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