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MYP_071710
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Basic Information
Brevinin-2GHa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
33 amino acids
C153H243N43O42S2
Standard
Sequence
GFSSLFKAGAKYFLKQVGKAGAQQLACKAANNC
Physicochemical Analysis
3420.96 Da
9.79
4.73
4.49
0.1435
0.00
0.62
0.09
21.27
65.45
0.1212
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1400.76
-15.92
49.0
49.0
117.0
240.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001397 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0004507 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
7.8 μg/mL
MIC
Paper沼水蛙抗菌肽brevinin-2GHa1分离纯化及结构分析; Purification and Structure Analysis of an Antibacterial Peptide Brevinin-2GHa1 from Skin Secretion of Hylarana guentheri. [J].中国生物化学与分子生物学报,2014,30(11):1126-1132. DOI:10.13865/j.cnki.cjbmb.2014.11.11. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37199
RECORD: Rec_0060758 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
3.9 μg/mL
MIC
Paper沼水蛙抗菌肽brevinin-2GHa1分离纯化及结构分析; Purification and Structure Analysis of an Antibacterial Peptide Brevinin-2GHa1 from Skin Secretion of Hylarana guentheri. [J].中国生物化学与分子生物学报,2014,30(11):1126-1132. DOI:10.13865/j.cnki.cjbmb.2014.11.11. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37199
RECORD: Rec_0088329 VERIFIED: NO
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0164903 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
2 μg/mL
MIC
Paper沼水蛙抗菌肽brevinin-2GHa1分离纯化及结构分析; Purification and Structure Analysis of an Antibacterial Peptide Brevinin-2GHa1 from Skin Secretion of Hylarana guentheri. [J].中国生物化学与分子生物学报,2014,30(11):1126-1132. DOI:10.13865/j.cnki.cjbmb.2014.11.11. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37199
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