Peptide Database

Peptide NameHNH nuclease (Pyocin-S2 (EC 3.1.-.-))

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length662 amino acids

Chemical FormulaC3156H5064N872O990S15

DescriptionStandard

        MAVNDYEPGSMVITHVQGGGRDIIQYIPARSSYGTPPFVPPGPSPYVGTGMQEYRKLRSTLDKSHSELKKNLKNETLKEVDEIKSEAGLPGKAVSANDIRDEKSIVDALMDAKAKSLKAIEDRPANLYTASDFPQKSESMYQSQLLASRKFYGEFLDRHMSELAKAYSADIYKAQIAILKQTSQELENKARSLEAEAQRAAAEVEADYKARKANVEKKVQSELDQAGNALPQLTNPTPEQWLERATQLVTQAIANKKKLQTANNALIAKAPNALEKQKATYNADLLVDEIASLQARLDKLDAETARRKEIARQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPLKTGPESYPGMLLDLNDLIVIFPADSGVKPVYVMLSSPLDSGIFTRRQLQKKFDSHKYDFGLGEKSANNGTLAEFRDKILEHLADPATVEKGTYHSEVNSKVHYNARTNIVVIIGEDGMFVSGWRIEPGTDQYNFYMKNEVL
    

Molecular Weight71544.19 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.81

Net Charge (pH 7.4) -1.57

Charge Density (pH 7.0) -0.0012

GRAVY Index-0.34

Hydrophobic Moment 0.65

Boman Index-0.00

Instability Index39.81

Aliphatic Index 84.09

Aromaticity 0.0619

Extinction Coeff. Reduced 59250.00

Extinction Coeff. Oxidized 59250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012497 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas aeruginosa [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal