MYP_071689
Basic Information
PG-1 analog 6
Antimicrobial
Standard
18 amino acids
C105H159N35O22
Standard
Sequence
RGGRLWYTRPRFTVWVGR
Physicochemical Analysis
2263.61 Da
12.00
4.76
4.55
0.2644
-0.82
0.58
-0.27
17.10
53.89
0.2222
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
951.00
-6.88
38.0
27.0
68.0
162.0
7.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119998 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that this sequence is unique and shows only very low similarity (72.22%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
vancomycin-resistant E. faecium A634
25 μg/mL
MIC
RECORD: Rec_0151693 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that this sequence is unique and shows only very low similarity (72.22%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
penicillin-resistant Staphylococcus aureus 1206
>200 μg/mL
MIC
RECORD: Rec_0237403 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that this sequence is unique and shows only very low similarity (72.22%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
Bacillus subtilis BR151
25 μg/mL
MIC
RECORD: Rec_0416860 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protegrin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that this sequence is unique and shows only very low similarity (72.22%) to PG-1 R: 28%, W=G: 17%, V: 11%. Chemical modification: central proline is a D-amino acid
Bio-Activity Profile
Antimicrobial
Escherichia coli JM109
6.3 μg/mL
MIC